Years ago, I played a lot of the Lord of the Rings LCG. Still have it and a billion expansions, that someday I'll have time to get to.
For game nights (not that I've had one of those in years either), Chaos in the Old World, Twilight Imperium, Blood Bowl Card Game, Acquire, some others are favorites. I have friends (with no kids) that still play all the time and rave about stuff like Gloomhaven.